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Acute myeloid leukemia discovery tackles drug-resistant gene mutations

Although it’s considered a rare cancer, acute myeloid leukemia is one of the most common types of leukemia in adults.

Addressing NGS challenges

What are some of the most difficult clinical sample types for sequencing-related projects and why? Patient tissue is predominantly preserved as formalin-fixed, paraffin-embedded...
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Unlocking the potential of ctDNA-based MRD testing to improve cancer management

Over the past 20 years, clinical oncology practice has evolved in several important ways. Most excitingly, treatment strategies have become more personalized to the individual...
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Navigating the landscape of hepatitis B: Symptoms, causes, and testing

Hepatitis B virus (HBV), despite widespread vaccination efforts, poses a global health challenge affecting around 2 billion people worldwide.1 Chronic HBV contributes to 30% of...
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Building an effective QC system

Applying workforce considerations and asking the right questions are key to establishing lab QC protocols.
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The role of biomarkers in a prostate cancer diagnosis

Biomarkers serve as critical navigational tools, guiding physicians on their patients’ journey through the diagnosis, treatment, and management of their specific cancer....
Infectious Disease

Benefits of molecular test-and-treat for Group A Streptococcus pharyngitis

Group A streptococcal (GAS) infections have been on the rise since late 2022 and 2023 after an overall low incidence during the years of the COVID-19 pandemic.1  GAS infections...
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Information Technology

Preparing your laboratory for an extended downtime: Best practices and strategies

Clinical laboratories are now confronted with the growing risk of cybersecurity attacks and are grappling with the task of sustaining operational functionality in the face of ...

Patient self-testing and disease prevention

During the pandemic, I was tested for COVID-19 in a laboratory. This test really scared me. The lady testing me stuck the swab so far up my nose, I was afraid I was going to get...
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Existing drug shows promise as treatment for rare genetic disorder

NIH researchers find new pathways towards treatment for autoimmune polyendocrine syndrome type 1.
Online Exclusives

BD’s Molly Broache, Associate Director of U.S. Medical Affairs, discusses the current state of STI testing in the U.S. with MLO editor in chief, Christina Wichmann

Molly Broache serves as Associate Director, US Region, Medical Affairs for BD Diagnostic Solutions and is also licensed as a women’s health nurse practitioner in both Maryland...

Working to advance pathology practices

In the Medscape Physician Burnout & Depression Report: “We Have Much Work to Do” released earlier this year, forty-nine percent of physicians told Medscape they...
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Next-generation sequencing in laboratory medicine

Advancements in sequencing techniques and the emergence of next-generation sequencing (NGS) technology have transformed laboratory medicine and clinical diagnosis. DNA sequencing...

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Continuing Education

Applying laboratory quality principles to real world point-of-care testing systems

To take the test online go HERE. For more information, visit the Continuing Education tab. LEARNING OBJECTIVES Upon completion of this article, the reader will be able to: 1. ...

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Kids from disadvantaged communities may die sooner from cancerous brain tumors

Researchers say socioeconomic factors may affect a person’s ability to be diagnosed and treated.