New criteria for sepsis in children based on organ dysfunction

Jan. 26, 2024
Sepsis is a major public heath burden, claiming the lives of over 3.3 million children worldwide every year.

Clinician-scientists from Ann & Robert H. Lurie Children’s Hospital of Chicago were among a diverse, international group of experts tasked by the Society of Critical Care Medicine (SCCM) with developing and validating new data-based criteria for sepsis in children.

The new pediatric sepsis criteria – called the Phoenix criteria – follow the paradigm shift in the recent adult criteria that define sepsis as severe response to infection involving organ dysfunction, as opposed to an earlier focus on systemic inflammation. The new pediatric sepsis criteria and their development are presented in two papers published in JAMA on January 21, 2024, and concurrently announced at the SCCM Critical Care Congress in Phoenix, Arizona.

Ann & Robert H. Lurie Children’s Hospital of Chicago release on Newswise