Mayo Clinic neurosurgeon describes the latest options for treating epilepsy

Feb. 9, 2023
International Epilepsy Day is February 13.

Epilepsy is a neurological disorder in which brain activity becomes abnormal, causing seizures or periods of unusual behavior, sensations, and sometimes loss of awareness. Anyone can develop epilepsy and epilepsy affects males and females of all races, ethnic backgrounds and ages. In this expert alert, Jamie Van Gompel, M.D., a neurosurgeon at Mayo Clinic, describes the latest treatment options. 

In recent years, new treatment options for epilepsy, including minimally invasive options, have developed.  

The latest treatments include: 

  • Deep brain stimulation. This is the use of a device that is placed permanently deep inside the brain. The device releases regularly timed electrical signals that disrupt seizure-inducing activity. This procedure is guided by MRI. The generator that sends the electrical pulse is implanted in the chest. 
  • Responsive neurostimulation. These implantable, pacemaker-like devices can help significantly reduce how often seizures occur. These responsive stimulation devices analyze brain activity patterns to detect seizures as they start and deliver an electrical charge or drug to stop the seizure before it causes impairment. Research shows that this therapy has few side effects and can provide long-term seizure relief. This device is placed in the skull.  
  • Laser interstitial thermal therapy (LITT). This is less invasive than resective surgery. It uses a laser to pinpoint and destroy a small portion of brain tissue. An MRI is used to guide the laser. 
  • Minimally invasive surgery. New minimally invasive surgical techniques, such as MRI-guided focused ultrasound, show promise at treating seizures with fewer risks than traditional open brain surgery for epilepsy. 

Mayo Clinic release on Newswise