The U.S. Department of Health and Human Services (HHS) announced that up to 442,000 doses of the JYNNEOS vaccine will be available for states and jurisdictions to order under an accelerated Phase 3 of the National Vaccine Strategy (NVS) to combat the current monkeypox outbreak.
Under the original timeline for Phase 3, doses were to be made available for ordering in three segments released on July 29, August 15, and later in August. In light of the recent Food and Drug Administration (FDA) Emergency Use Authorization (EUA) and revised dosing guidelines from the Centers for Disease Control and Prevention (CDC), HHS is able to make both segments two and three available for ordering—double the number of doses as originally anticipated.
Under the FDA EUA for JYNNEOS, the vaccine may be injected intradermally (in the upper skin layer) for individuals 18 years of age and older who are determined to be at high risk for monkeypox infection – a change that increases doses by up to five-fold. States and jurisdictions can now access additional doses from the federal government through the NVS earlier than projected and expand use of vaccine they have already received. The intradermal method of injecting the vaccine is safe and produces a similar immune response to the subcutaneous method (underneath the skin).
