Ohio State participated in trial confirming efficacy of novel heart failure treatment

Dec. 8, 2022
Ohio State clinical trial.

The Ohio State University Wexner Medical Center randomized a patient in a clinical trial confirming the clinical benefit of a device designed to treat diastolic heart failure. The first patient was randomized Thursday in the multicenter, prospective, randomized, double blinded study (RESPONDER-HF) at Ohio State’s Richard M. Ross Heart Hospital.  

Ohio State randomized patients in the two prior clinical trials evaluating whether a dime-size implant relieved the high pressure and associated heart failure symptoms, created by blood backing up from the heart into the lungs.  

During the procedure, doctors insert a catheter into a vein in the groin to access the heart. The catheter creates a small path between the left and right upper chambers of the heart. Doctors insert the tiny, inter-atrial shunt device to keep the path open to divert some of the blood from the high pressure left atrial chamber to the low-pressure right atrial chamber. This lowers pressure in the left upper chamber, decreasing pressure in the lungs and improving symptoms of heart failure for some patients.  

The Ohio State University release

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