Thermo Fisher Scientific has introduced the Gibco Expi293 PRO Expression System, a next-generation HEK293 transient expression system designed to deliver exceptional protein yields for a wider variety of proteins, including low-yield and challenging proteins, with higher throughput and speed.
The Expi293 PRO Expression System offers exceptional yields, speeds and efficiencies for a wide range of proteins, enabling the expression of proteins that were previously unable to be expressed.
The Expi293 PRO Expression System is composed of a new, clonally derived HEK293 cell line, Gibco Expi293 PRO Cells, which can produce difficult-to-express proteins and support protein production on a milliliter to multi-liter scale. Additionally, the system includes Gibco Expi293 Medium, an optimized culture medium, and Gibco Expi293 PRO Transfection Kit, which enables high-density cell transfection. It also includes components and protocols designed for easy incorporation into automated workflows and a streamlined protocol to minimize hands-on time and maximize the number of transfections that can be performed per week.
Together, these optimized components enable the Expi293 PRO Expression System to produce significant improvements in protein yields across a broad range of proteins. The system also offers a more sustainable protein expression solution, featuring greener packaging and helping to reduce plastic consumption, reagent consumption and labor by at least 3-fold.
“Achieving sufficient yields of difficult-to-express proteins remains a major challenge for scientists, often slowing down critical research and drug discovery while increasing time, labor and cost,” said Tiffani Manolis, Vice President and General Manager, Cell Biology, Thermo Fisher Scientific. “Built on the trusted legacy of our Expi293 products, the Gibco Expi293 PRO Expression System was developed to meet evolving demands, from high-throughput screening in 96-well plates to liter-scale production. As protein targets grow more complex, researchers need a system that offers both flexibility and efficiency across diverse protein classes. Expi293 PRO helps overcome expression bottlenecks, accelerating scientific progress and ultimately improving global health outcomes.”
*FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES.
