June 2015 Product Focus – VITAMIN D

June 18, 2015

Beckman Coulter’s new ACCESS 25(OH) VITAMIN D TOTAL ASSAY provides laboratories with the tools needed to confidently diagnose vitamin D deficiency or insufficiency.  Laboratories will benefit with (1) confidence in patient results through standardization to the gold standard 25(OH) Vitamin D Reference Measurement Procedure (RMP) from Ghent University; (2) accurate clinical assessment of vitamin D status provided by measurement of total 25(OH) vitamin D with equimolar measurement of 25(OH) vitamin D2 and 25(OH) vitamin D3; (3) excellent stability and reproducibility with greater storage convenience from an opaque reagent pack designed to prevent light-induced reagent degradation and (4) optimal productivity for both low and high-volume laboratories using the UniCel DxI and Access 2 Immunoassay Systems.
Visit: www.beckmancoulter.com/VitD

Bio-Rad’s New Specialty Immunoassay Controls

Bio-Rad’s Liquichek and Lyphochek Specialty Immunoassay Controls are formulated control materials that can provide values for 25-OH Vitamin D2, D3, and Total Vitamin D. Both controls can be used on major automated instruments, as well as LC/MS methods. Long shelf life and open-vial stability allows users to monitor assay performance across multiple reagent lots as well as effective utilization of the control material.

Visit: www.bio-rad.com/en-us/product/liquichek-specialty-immunoassay-control

DiaSorin’s LIAISON 25 OH Vitamin D TOTAL assay and their new LIAISON XL 1,25 Dihydroxyvitamin D Assay

The DiaSorin LIAISON 25 OH Vitamin D TOTAL Assay is a fully automated assay measuring both D2 and D3 for a total result. DiaSorin Vitamin D assays have been used for major national studies such as the Nurse Health Study (NHANES), and have been utilized in clinical studies worldwide. The LIAISON 25 OH Vitamin D TOTAL Assay is certified with the Vitamin D Standardization Program (VDSP). The DiaSorin Assay met the VDSP requirements and no adjustments to the assay or its calibrations were needed. The VDSP is a collaborative initiative organized by the Office of Dietary Supplements of the NIH to help standardize 25 OH Vitamin D measurements across methods. To ensure accurate measurement, all Vitamin D assays should be standardized.

The new LIAISON XL 1,25 Dihydroxyvitamin D assay is an extraction-free, fully automated 1,25 dihydroxyvitamin D assay. The LIAISON XL 1,25 Dihydroxyvitamin D assay eliminates the extraction step, providing higher throughput and a faster time-to-first result of only 65 minutes. The assay is a chemiluminescent immunoassay for the quantitative determination of 1,25 dihydroxyvitamin D in serum and offers excellent precision, accuracy and sensitivity. It will allow laboratories with LIAISON XL Analyzers to run the LIAISON 25 OH Vitamin D TOTAL Assay, LIAISONN-TACT PTH Gen II and LIAISON XL 1,25 Dihydroxyvitamin D together on one instrument utilizing a single serum sample tube.

Visit: www.diasorin.com/en/liaisonr-xl-125-dihydroxyvitamin-d

Randox’s Advanced Vitamin D Testing with Quality Control

With over one billion people worldwide suffering from Vitamin D deficiency, the need for reliable test results and accurate diagnosis has never been more apparent. Randox Quality Control has a wide range of QC solutions to meet the needs of every laboratory. The Immunoassay Premium Plus Control offers extensive consolidation, combining over 54 analytes including vitamin D, tumor markers, therapeutic drugs and hormones. Available in three concentrations covering the full clinical range, it offers stability that ensures accurate test results and ultimately, cost savings. All Randox immunology based tests meet the requirements set out in ISO 15189. Reacting in the same manner as a patent sample, this 100% human control is highly commutable.

Visit: www.randox.com/quality-control/immunoassay-controls/immunoassay-controls

Siemens ADVIA Centaur Vitamin D Total Assay

The ADVIA Centaur Vitamin D Total Assay from Siemens Healthcare Diagnostics is a fully equimolar, automated total 25(OH) vitamin D (~100% D2 and D3) assay employing a proprietary monoclonal with minimal 1.1% 3-epi-25(OH) vitamin D3 cross-reactivity aligned to the ID-LC/MS/MS 25(OH) vitamin D Reference Measurement Procedure (RMP), the reference procedure for the Vitamin D Standardization Program (VDSP). This assay can be combined with routine, stat, and specialty assays without compromising time. Results are provided in as little as 18 minutes with a throughput of 240 tests per hour. Laboratories can meet increased testing demands by consolidating vitamin D testing on a fully automated, high-throughput immunoassay system.

Visit: http://www.healthcare.siemens.com/clinical-specialities/bone-metabolism/advia-centaur-vitamin-d-total-assay