Cerilliant has introduced seven new Certified Spiking Solutions of bath salt metabolites. The new products are 1.0 mg/mL (as free base) in methanol for the primary urinary metabolites of bath salt cathinones, mephedrone, buphedrone, pentedrone, flephedrone, N-ethylcathinone, and 4-methylethcathinone. For GC/MS and LC/MS methods that quantify concentrations of synthetic cathinone metabolites, Cerilliant also offers the corresponding deuterium-labeled internal standard to compliment this new line of certified reference solutions.
Metabolism of synthetic cathinones presents significant challenges to the analytical laboratory. Routine screening of parent synthetic cathinones by GC/MS or LC/MS is not always sufficient to identify a positive result, because many of the parent drugs are extensively converted to reduced or dealkylated metabolites. Some laboratories have reported a substantial number of specimens that contain reduced metabolites of synthetic cathinones, but no trace of the parent drugs. In these cases, screening user samples for the presence of the metabolites would be critical to confirm a positive result.
“The synthetic cathinone metabolites product line provides our customers additional certified solution standards for their bath salt testing methods, especially for cases where the user samples may only contain the metabolites and no parent drug,” states Derrell Johnson, Cerilliant’s New Product Development Manager. Learn more about products provided by Cerilliant.