Some healthcare workers produced a low response to COVID-19 vaccinations in a study by Cedars-Sinai
A subset of healthcare workers vaccinated against COVID-19 had unexpectedly low responses to the immunizations, according to Cedars-Sinai investigators. The findings of the new study are published in iScience, a Cell Press journal.
In a matched control study, investigators compared the vaccine responses among a group of Cedars-Sinai healthcare workers who were generally in good health. The study participants received the BNT162b2 vaccine produced by Pfizer Inc., and their average age was 48.
Investigators noted that the “low responders” in the study were relatively young, but their immune systems reacted to the vaccine as if they were much older.
This study is part of the ongoing Coronavirus Risk Associations and Longitudinal Evaluation (CORALE) project led by Cedars-Sinai. Investigators say this study finding of a low vaccine response among otherwise healthy people requires further research.
