New England Biolabs (NEB) announced the release of the Monarch Mag Cell-free DNA (cfDNA) Extraction Kit, which enables consistent, scalable extraction of low-abundance, circulating cell-free DNA (cfDNA) for downstream applications including biomarker discovery and diagnostics development.
The magnetic, bead-based workflow is compatible with biofluids including plasma, serum, urine and cerebrospinal fluid across variable input volumes from 1ml to 4 ml.
The kit design and format offers maximum versatility across sample number, input amounts, and sample types. Whether users are manually handling a couple of samples or processing a higher throughput with the support of automation, they can expect consistent recovery of concentrated cfDNA across the full range of fragment sizes, down to 50 base pairs in length. Aligned with the broader Monarch portfolio, the kit reduces plastic usage in reagent bottles and packaging components as compared to standard market solutions.
The Monarch Mag Cell-free DNA (cfDNA) Extraction Kit pairs with NEB’s downstream amplification and library prep products, including the NEBNext portfolio for next generation sequencing library preparation.
Visit NEB for more information
