Foundation laid for improved diagnostic imaging of brain tumors

Jan. 16, 2024
Research team draws up criteria for PET-based examinations of malignant brain tumors.

An international team of researchers (RANO Working Group), led by scientists from LMU and the Medical University of Vienna, has now drawn up international criteria for the standardized imaging of gliomas using amino acid PET. It has published its results in the journal The Lancet Oncology.

Under the joint leadership of nuclear physician Nathalie Albert from LMU and oncologist Professor Matthias Preusser from the Medical University of Vienna, the RANO group has developed new criteria for assessing the success of therapies for diffuse gliomas. These malignant brain tumors develop out of glial cells in the brain. Tumors of this kind are generally aggressive and difficult to treat. The RANO group has developed criteria that permit evaluation of the success of treatment using positron emission tomography (PET). Called PET RANO 1.0, these PET-based criteria open up new possibilities for the standardized assessment of diffuse gliomas.

According to the researchers, the new criteria allow PET to be used in clinical studies and everyday clinical practice and create a foundation for future research and the comparison of treatments for improved therapies.

Ludwig-Maximilians-Universität München (Munich) release on Newswise