Thermo Fisher Scientific introduces next-generation unmixing beads to enhance accuracy and performance in spectral and conventional flow cytometry

Sept. 8, 2025

Thermo Fisher Scientific has introduced Invitrogen UltraComp eBeads Spectral Unmixing Beads to improve accuracy in spectral and conventional flow cytometry.

These beads help researchers more accurately separate overlapping fluorescent signals, making it easier to distinguish many cell types quickly, track rare cells and achieve consistent performance across experiments.  

Researchers who use flow cytometry as a tool for analyzing cellular phenotypes and functions require deeper insights into cells to better understand disease and discover targeted therapies. Spectral and high-parameter flow cytometry can provide a more comprehensive view of many cell types, but current solutions can lead to false positives and negatives, as well as background interference that limits analysis. UltraComp eBeads behave like real cells, reduce autofluorescence and enhance fluorochrome signal clarity, leading to more precise results.  

Key features:

  • Unmixing and compensation performance comparable to real cells
  • Improved unmixing accuracy
  • Bright and consistent fluorophore signals and reduced fluorescence background noise
  • Multispecies compatibility
  • Supports all major laser lines: UV, violet, blue, green, yellow-green, red and IR
  • Easy setup: Each drop contains both positive and negative populations, creating two distinct peaks that make it easier to prepare—even for high-parameter panels

Visit Thermo Fisher Scientific for more information

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