In a new study, researchers wanted to know whether blood-brain barrier impairment contributed to the development of neurological problems during COVID-19 progression, and to what extent.
The findings demonstrate that “COVID-19-associated blood plasma inflammatory factors do not affect blood-brain barrier paracellular pathway directly,” the researchers wrote. In addition, the results suggest “pathological remodeling, if any, of the blood-brain barrier during COVID-19 may occur through indirect or yet unknown mechanisms.” The study is published in the journal Function.