IDT and Illumina collaborate to strengthen somatic oncology research

The collaboration will combine IDT’s library prep with Illumina’s DRAGEN platform to speed up somatic oncology research and improve data reliability, especially for challenging FFPE samples.

Danaher company Integrated DNA Technologies (IDT) and Illumina have entered into a strategic partnership aimed at streamlining somatic oncology research. The collaboration will enable a DRAGEN secondary analysis pipeline for IDT xGen FFPE and cfDNA next generation sequencing (NGS) library preparation with custom panels.

By connecting IDT’s library prep with Illumina’s DRAGEN secondary analysis platform, researchers can reduce downstream burden and accelerate the path from sequencing to insight with greater speed and consistency.

IDT’s xGen FFPE and cfDNA workflows already support hundreds of thousands of samples annually, and this collaboration is designed to reduce the NGS analysis burden by streamlining the journey from sample to insights for oncology researchers. The DRAGEN Somatic for IDT Custom Panels was designed for use with IDT library prep workflows and optimized for challenging FFPE samples with a new, low-quality FFPE mode. This integrated workflow ensures that researchers can collect more reliable insights from degraded oncology research samples. 

The collaboration brings IDT's library prep solutions into Illumina's extensive software ecosystem, enabling streamlined analysis for IDT's FFPE and cfDNA workflows while reducing hands-on data processing steps. Initial workflows, available now, focus on FFPE samples. A version of the joint workflow, optimized toward cfDNA liquid biopsy targeted applications, will be available next year. Data analyzed in DRAGEN Somatic for IDT Custom Panels is designed for compatibility with Illumina's flagship variant interpretation platform, Illumina Connected Insights, for streamlined reporting of somatic oncology variants.

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