Improving nucleic acids purification from clinical genomic samples

Nov. 11, 2019

Purigen Biosystems, a provider of next-generation technologies for extracting and purifying nucleic acids from biological samples, announced the launch of its Ionic Purification System.

The small benchtop system utilizes the company’s core isotachophoresis (ITP) technology to extract, purify, and concentrate nucleic acids from biological samples in one hour with less than three minutes of hands-on time per sample. Purigen will unveil the new system and present data during (AMP) 2019 Annual Meeting and Expo.

Purigen will present data and showcase its new Ionic Purification System in booth #3139 at the Association for Molecular Pathology (AMP) 2019 Annual Meeting in Baltimore on November 7-9, 2019.

The Ionic Purification System enables the automated extraction of nucleic acids with dramatically increased yields and improved purity from a wide range of sample types, including cultured or sorted cells and formalin-fixed, paraffin-embedded (FFPE) tissues. Biological samples are gently lysed and then loaded into the Ionic Fluidics Chip. The Ionic system then applies an electric field to the chip and the nucleic acids are isolated in their natural, native form using the company’s proprietary ITP technology. The nucleic acids are not denatured or dehydrated, and there is no binding or stripping from fixed surfaces. The process minimizes fragmentation and eliminates any bead or buffer contamination. The extracted nucleic acids are pure, abundant, and ready for analysis by any downstream technique such as next-generation sequencing or PCR.

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