Certain genes will not increase cancer mortality risk

March 28, 2025

New University of Michigan Rogel Cancer Center results could provide peace of mind to certain breast, pancreatic, and colorectal cancer patients.

According to a release, germline genetic testing can help patients determine their cancer mortality risk. ATMCHEK2 and PALB2 gene mutations do not increase a patient's risk of dying from the three cancers. “The risk of dying from breast, colorectal or pancreatic cancer was the same for patients with ATMCHEK2 or PALB2 variants as for those without any genetic variant.”

The study is published in the Journal of Clinical Oncology.

Michigan Medicine release on Newswise