AMP releases series of reports defining core bioinformatics competencies for clinical diagnostic laboratories
The Association for Molecular Pathology announced the release of a three-part series of scientific papers outlining the essential bioinformatics roles, responsibilities, and competencies for professionals working in clinical molecular diagnostic laboratories.
The series, titled “Clinical Bioinformatician Body of Knowledge: A Report of the Association for Molecular Pathology,” was published online ahead of print, and the full text is freely available in The Journal of Molecular Diagnostics.
The Body of Knowledge series represents the collaborative work of three subject matter expert working groups convened by AMP. Each paper focuses on key domains required for a bioinformatician to function successfully within a molecular diagnostic laboratory and is based upon the published scientific evidence, available resources, established clinical practices, and expert consensus opinions of the working groups. AMP plans to periodically review and update the framework to ensure that it remains relevant and actionable.
The three core knowledge areas covered in this series are as follows:
- Molecular Diagnostics: A comprehensive overview of key concepts in molecular biology, genetic variation, molecular diagnostics methodologies (with an emphasis on next-generation sequencing) and best practices in clinical laboratory operations
- Clinical Bioinformatics and Software: A detailed look at the stages of a clinical bioinformatics pipeline development, validation, and deployment, including associated skill sets and software development best practices required throughout the process
- Clinical Laboratory Regulation and Data Security: An examination of relevant regulatory requirements and best practices related to data security in laboratory environments, including hardware, software, networks and interoperability
To read AMP’s perspective article on the complete Body of Knowledge series, please visit https://www.jmdjournal.org/article/S1525-1578(24)00315-5/fulltext.
