CHOP develops AI guidelines for pediatric neuro-oncology

These new guidelines aim to foster ethical AI deployment in pediatric neuro-oncology, guiding clinicians on techniques, reporting standards, and the importance of unbiased, precise AI tools for better patient care.
Oct. 29, 2025

A group of scientists from Children’s Hospital of Philadelphia (CHOP) has developed new guidelines that outline artificial intelligence (AI) best practices in pediatric neuro-oncology. Key recommendations are summarized in a press release.

The goal of this action is to foster the responsible use of AI in pediatric neuro-oncology settings. Elements of the guidance are “a policy review from the AI in Response Assessment in Pediatric Neuro-Oncology (AI-RAPNO) subcommittee and a companion review in The Lancet Oncology, detailing how AI can enhance tumor assessment, support treatment planning and improve outcomes for children with brain tumors.”

AI-RAPNO suggests:

  • Be specific; use “standardized imaging inputs and labels”
  • Make sure techniques aren’t biased
  • Thoroughly report results and take “the limits and accuracy of the techniques” into account
  • Review clinical trials

About the Author

Erin Brady

Managing Editor

Erin Brady is Managing Editor of Medical Laboratory Observer.

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