Gender differences in cancer outcomes: Insights from a large-scale study

Research conducted by Adelaide University and partners shows women experience more severe side effects by 12%, despite better overall survival, emphasizing the need for personalized cancer care strategies.
March 17, 2026

A recent study of more than 20,000 patients with varying cancers found differences in the way cancer effects women over men. The findings are reported in a press release.

The research was performed by Adelaide University scientists and their international partners leveraging records from 39 clinical trials that led to U.S. Food and Drug Administration (FDA) approvals in 2011-2021. Key findings:

  • Women had 21% higher longevity than men
  • Female patients’ cancers were 16% less likely to progress
  • Severe side effects were 12% more common in women

These findings were comparable across all 12 cancer types studied, despite the patient’s treatment pathway. The authors hope their findings are used to inform personalized care. The study is published in the Journal of the National Cancer Institute. 

About the Author

Erin Brady

Managing Editor

Erin Brady is Managing Editor of Medical Laboratory Observer.

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