The World Health Organization is launching a global scientific process to update the list of priority pathogens—agents that can cause outbreaks or pandemics—to guide global investment, research and development (R&D), especially in vaccines, tests and treatments.
Starting with a meeting held last Friday, November 18, WHO is convening over 300 scientists who will consider the evidence on over 25 virus families and bacteria, as well as “Disease X.” Disease X is included to indicate an unknown pathogen that could cause a serious international epidemic. The experts will recommend a list of priority pathogens that need further research and investment. The process will include both scientific and public health criteria, as well as criteria related to socioeconomic impact, access, and equity.
For those pathogens identified as priority, the WHO R&D Blueprint for epidemics develops R&D roadmaps, which lay out knowledge gaps and research priorities. Where relevant, target product profiles, which inform developers about the desired specifications for vaccines, treatments and diagnostic tests, are developed. Efforts are also made to map, compile and facilitate clinical trials to develop these tools. Complimentary efforts – such as to strengthen regulatory and ethics oversight – are also considered.
The revised list is expected to be published in the first quarter of 2023.
