Chronic diseases make up more of the top causes of death

Dec. 10, 2020

Chronic, or noncommunicable, diseases now make up seven of the world’s top 10 causes of death – up from 4 out of 10 in 2000, according to the World Health Organization (WHO) in its 2019 Global Health Estimates report.

The new data cover the period from 2000 to 2019.

“These new estimates are another reminder that we need to rapidly step-up prevention, diagnosis and treatment of noncommunicable diseases,” said Tedros Adhanom Ghebreyesus, PhD, Director-General of WHO. “They highlight the urgency of drastically improving primary health care equitably and holistically. Strong primary health care is clearly the foundation on which everything rests, from combatting noncommunicable diseases to managing a global pandemic.”

Heart disease has remained the leading cause of death at the global level for the last 20 years. However, it is now killing more people than ever before. The number of deaths from heart disease increased by more than 2 million since 2000, to nearly 9 million in 2019. Heart disease now represents 16 percent of total deaths from all causes. More than half of the 2 million additional deaths were in the WHO Western Pacific region. Conversely, the European region has seen a relative decline in heart disease, with deaths falling by 15 percent.

Alzheimer’s disease and other forms of dementia are now among the top 10 causes of death worldwide, ranking 3rd in both the Americas and Europe in 2019. Women are disproportionally affected: globally, 65 percent of deaths from Alzheimer’s and other forms of dementia are women.

Deaths from diabetes increased by 70 percent globally between 2000 and 2019, with an 80 percent rise in deaths among males. In the Eastern Mediterranean, deaths from diabetes have more than doubled and represent the greatest percentage increase of all WHO regions.

In 2019, pneumonia and other lower respiratory infections were the deadliest group of communicable diseases and together ranked as the fourth leading cause of death. However, compared to 2000, lower respiratory infections were claiming fewer lives than in the past, with the global number of deaths decreasing by nearly half a million.

This reduction is in line with a general global decline in the percentage of deaths caused by communicable diseases. For example, HIV/AIDS dropped from the 8th leading cause of death in 2000 to the 19th in 2019. While it remains the fourth leading cause of death in Africa, the number of deaths has dropped by more than half, falling from over 1 million in 2000 to 435 000 in 2019 in Africa.

The report also shows a growing trend for longevity. In 2019, people were living more than 6 years longer than in 2000, with a global average of more than 73 years in 2019 compared to nearly 67 in 2000. But on average, only 5 of those additional years were lived in good health.

Indeed, disability is on the rise. To a large extent, the diseases and health conditions that are causing the most deaths are those that are responsible for the greatest number of healthy life-years lost. Heart disease, diabetes, stroke, lung cancer and chronic obstructive pulmonary disease were collectively responsible for nearly 100 million additional healthy life-years lost in 2019 compared to 2000.

Injuries are another major cause of disability and death: there has been a significant rise in road traffic injuries in the African region since 2000, with an almost 50 percent increase in both death and healthy life-years lost. Similar but slightly smaller increases (at around 40 percent) were also observed for the Eastern Mediterranean region. Globally, deaths from road traffic injuries are 75 percent male.

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