Glutamic Acid Decarboxylase Autoantibody (GADAb)

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The KRONUS Glutamic Acid Decarboxylase Autoantibody (GADAb) ELISA Assay Kit is for the semi-quantitative determination of glutamic acid decarboxylase antibody in human serum, and is useful as an aid in the diagnosis of Type 1 diabetes mellitus (autoimmune mediated diabetes).

Diabetes mellitus is generally classified as either Type 1 (insulin dependent diabetes mellitus) or Type 2 (non-insulin dependent diabetes mellitus). In most instances, the onset of type 1 diabetes (IDDM) is the result of autoimmune destruction of insulin-producing beta cells in the pancreatic islets and the ensuing loss of endogenous insulin secretion.

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