Zinc Transporter 8 Autoantibody (ZnT8Ab)

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The KRONUS Zinc Transporter 8 Autoantibody  (ZnT8Ab) ELISA Assay is for the semi-quantitative determination of autoantibodies to Zinc Transporter 8 (ZnT8) in human serum, and may be useful as an aid in the diagnosis of Type 1 diabetes mellitus (autoimmune mediated diabetes). The ZnT8Ab assay is not to be used alone and is to be used in conjunction with other 
clinical and laboratory findings.

Type 1 diabetes mellitus (T1DM) is the result of autoimmune destruction of the insulin-producing β cells in the pancreatic islets and subsequent 
loss of insulin secretion. Measurement of islet autoantibodies has become a useful clinical tool for the diagnosis of patients with diabetes.

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