To download Pediatric Reference Intervals, click here. 

The information in this chart was updated by MLO Staff based on the CALIPER database¹ and reviewed by Khosrow Adeli, PhD, FCACB, DABCC, FADLM, Head, Clinical Biochemistry at The Hospital for Sick Children and Principle Investigator of the CALIPER Program. The reviewed chemistries are comparable to those listed in MLO's original Pediatric Reference Intervals chart, last updated in 2022. For reference intervals obtained by other lab instruments, see the CALIPER database.¹

References

1. CALIPER Pediatric Reference Interval Database. CALIPER. Accessed May 20, 2025. https://caliper.research.sickkids.ca/#/.
2. Colantonio DA, Kyriakopoulou L, Chan MK, et al. Closing the gaps in pediatric laboratory reference intervals: a CALIPER database of 40 biochemical markers in a healthy and multiethnic population of children. Clin Chem. 2012;58(5):854-868. doi:10.1373/clinchem.2011.177741.
3. Tahmasebi H, Higgins V, Woroch A, Asgari S, Adeli K. Pediatric reference intervals for clinical chemistry assays on Siemens ADVIA XPT/1800 and Dimension EXL in the CALIPER cohort of healthy children and adolescents. Clin Chim Acta. 2019;490:88-97. doi:10.1016/j.cca.2018.12.011. 
4. Higgins V, Asgari S, Chan MK, Adeli K. Pediatric reference intervals for calculated LDL cholesterol, non-HDL cholesterol, and remnant cholesterol in the healthy CALIPER cohort. Clin Chim Acta. 2018;486:129-134. doi:10.1016/j. cca.2018.07.028.