The Impact of 25G UltraTouch™ Collection Set on Sample Quality

Specimens collected from oncology patients using BD Vacutainer® UltraTouch™ Push Button system with a 25G needle had significantly lower plasma hemoglobin values versus a 23G needle, indicating that a smaller needle did not compromise sample quality.
Sept. 9, 2025

This study evaluated oncology patients’ preferences and specimen quality outcomes when comparing two phlebotomy devices: the 23-gauge Standard BD Vacutainer Push Button Blood Collection Set and the 25-gauge BD Vacutainer UltraTouch Push Button Blood Collection Set. Frequent venipunctures in oncology patients often cause scarring and pain, making device choice especially important.

Study Design:

  • 101 oncology outpatients recruited; 89 completed preference analysis.
  • Each subject had two randomized, blinded blood draws—one with each device.
  • Specimen quality measured by plasma hemoglobin, lactate dehydrogenase (LDH), and potassium.

Key Findings:

  • Patient Preference:
  • 57% (51 patients) preferred the 25-gauge UltraTouch.
  • 34% (30 patients) preferred the 23-gauge Standard.
  • 9% (8 patients) reported no preference.
  • Results were statistically significant (P = 0.0196).

Specimen Quality:

  • UltraTouch samples had significantly lower plasma hemoglobin (5.34 mg/dL vs 9.37 mg/dL; P < 0.0001), indicating less hemolysis.
  • No significant differences in LDH or potassium levels between devices.

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