Cover Story

Next generation sequencing in the clinical molecular diagnosis of cancer: Advantages and challenges to clinical laboratory implementation
By Jeanne M. Rhea, PhD, Harsh Vardhan Singh, PhD, and Ross J. Molinaro, PhD, MT(ASCP), DABCC, FACB

PLUS  Cytokines: utility and laboratory measurement
By Masih Shokrani, PhD, MT(ASCP)

Features

Lab Management

Laboratory-driven Lean Sigma to prove critical to hospitals’ future success under new healthcare reform law
Clinical laboratories can apply Lean Sigma to enhance their operations and align with their institution’s objective of providing high-quality, cost-effective care.
By Patrick Maul

Education and Training

Redefining middleware: maximize your investment and increase quality
New and innovative applications of middleware are helping laboratories answer the question: “What can middleware do for us?”
By Hunter Bagwell

PLUS  Auto-validation: what’s your number?
By Anne Tate

PLUS  Middleware for the physician office laboratory
By Scott Lavine

Clinical Issues

Evolving research methods in cytology
With laser-scanning imaging cytometry continually evolving, the versatility and application repertoire of this technology will enhance research.
By Wendy Gaisford, PhD

Current Buzz

Immunoassays, drugs-of-abuse screening, and quality assurance
By Kathy Ruzich

PLUS  Rapid Testing: Simple and Effective
By Kerry Davies Pierce, MS

Executive Snapshot

Under Dr. G, DRG International gives medical and research companies an edge
By Alan Lenhoff

Departments

From the Editor

Someone you should know
By Alan Lenhoff

The Observatory

News/Trends/Analysis

Columns

Tips from the Clinical Experts

The quest for the $500 home molecular biology laboratory
By John Brunstein, PhD

Washington Report

Clinical laboratory developed tests: a 21st century approach
By Alan Mertz, MA

Liability and the Lab

Temperature measurement in the clinical laboratory…good enough isn’t good enough
By Robert Bove’

Product Focus

Genetic Testing